Innovations are a vital part to the physical and operating framework of the modern world. Technological advancements have made it possible to better the world and provide humanity with access to resources that were previously inaccessible. Whether it’s scientific breakthroughs in cancer research, or radar technology for submarines, innovation has been the success of civilization.
The field of medicine has made some of the most important breakthroughs in regards to medical technology. Revolutionizing healthcare, cutting edge trends are the result of the widespread use of laparoscopic surgery, artificial intelligence for diagnostics, and more. As the world changes, the advancements in technology seem to infiltrate every facet of life.
Self-proclaimed to be the future of personalized medicine, Chrono Therapeutics is transforming how medicine is delivered. By taking a unique approach, the people behind the company understand that successful therapy is not easy, and that hard-to-treat conditions require a non-traditional approach. Chrono Therapeutics is building a next generation, transdermal drug delivery device that combines biologically-timed drug delivery with personalized digital support. Based on groundbreaking technology, the company is helping people manage their conditions while achieving optimal clinical outcomes. Not only is this device revolutionary, but it promises a significant improvement in quality of life.
About Chrono Therapeutics
Chrono Therapeutics is committed to treating difficult conditions effectively. By utilizing transdermal drug delivery, they have revolutionized medical treatment. With decades of experienced combined, the team behind Chrono Therapeutics are experts in research, behavioral science, FDA approval, and product development. Possessing a myriad of skills and knowledge, the team is prepared to define the future of medication delivery.
Along with the team, Chrono Therapeutics has assembled some of the world's leading experts on transdermal drug delivery, smoking cessation, pharmaceutical commercialization, in order to guide the activities of the company. The experts make up the board of directors, as well as the scientific advisory board.
By creating a new medication delivery system, Chrono Therapeutics has utilized medication patches – made to deliver drugs transdermal, through the skin. By providing a steady dose of the drug throughout the day, it does not depend on whether or not the patient is exhibiting symptoms. Chrono Therapeutics' drug delivery system is made smarter – it provides the exact amount of medication needed, timed to when the patients' symptoms are the strongest. With their groundbreaking technology, the drug delivery system is personalized, making it more effective, as it only delivers medication as it is most needed.
How Chrono Therapeutics Works
The actual term “chrono” refers to the astute observation that each metabolic event goes through rhythmic changes in time. With certain diseases and illnesses, such as asthma, arthritis, ulcers, sleep disorders, and depression, and allergic rhinitis. The functions of the body vary from day to day, which can eventually cause disease and illnesses. Because the body follows the solar and lunar cycles, it is referenced as a biological clock or circadian rhythm. The human circadian rhythm is solely based on the sleep cycle, and can be influenced by many variables, such as genetics.
Because the functions of the body are always changing, during a 24-hour period, the body goes through many changes and is dependent on bodily functions. As hormones are released by the brain during the night and also first thing in the morning, blood pressure and heart rates are at the highest during the early morning, leaving the body vulnerable to dysfunction throughout the day.
The biological clock is so precise that if there is any disruption to the circadian rhythm, there could be significant trauma to the brain and behavior cognition. In the event of this happening, chronotherapeutics can be used in order to match the circadian rhythm and successfully treat the disease. For these treatments, medications are usually administered in the morning, because most symptoms occur during that time, however, Chrono Therapeutics takes a different approach, varying the times that the drug is administered based on individual needs.
Chronotherapeutic treatment is having so much impact on the medical field because it is an optimal method in treating patients as it requires specific medication administered at the target site, and with a specific concentration. The primary goal of transdermal drug delivery is to create a formulation that meets therapeutic needs that relate to a specific pathological system.
Chrono Therapeutics Philosophy
Focusing on smoking, Chrono Therapeutics examines smoking cessation. Most products use the same methodology, with no regard for individual lifestyle needs such as craving patterns, stressors, and smoking routines. Instead of treating all smokers the same, Chrono Therapeutics is taking a new approach by offering a comprehensive collection of personalized medication and behavioral tools that work together perfectly.
Smoking, a highly addictive habit, still remains one of the world's most deadly killers. There are over 40 million smokers in the United States and up to 70% of them are wanting to quit, however, the current treatment products on the market only work less than 10% of the time. Chrono Therapeutics is hoping to change that.
Aimed to be used in a 10-week program, the medication and behavioral tools are designed to help smokers quit – for good. The tools provide smokers with the knowledge and guidance needed to understand their addiction and overcome the cravings. Both physiological cravings, which is caused by the nicotine addiction, and the psychological cravings, often triggered by daily stress, such as being around smokers, are treated.
Chrono Therapeutics Flagship Product
In order to successfully treat patients, and designed to deliver the full potential of personalized medicine, Chrono Therapeutics combines four separate technologies, which are listed below.
Biologically-Timed Drug Delivery: Transdermal medication that is aimed at meeting individual patient needs.
Compliance Measurements: Utilizes embedded sensors as well as digital reminders in order to help patients stay on target while also keeping the care team in constant communication.
Behavioral support: Offers a personalized and proactive digital coaching and evidence based learning.
Data Analytics: Tracks trends and insights based on the patient population level in order to personalize therapy and explore insights.
By combining technology and medicine, Chrono delivers the transdermal nicotine timed at when the cravings are the strongest, minimizing the adverse symptoms of nicotine withdrawal, allowing smokers to focus on their recovery. Over 70% of smokers have their first cigarette within the first half hour of waking up. Chrono's nicotine replacement therapy solves the need for the morning craving by providing the support before the craving even hits. The system, worn throughout the night, is programmed to the smokers waking time, delivering nicotine before they get up for the day.
Chrono's nicotine delivery device is lightweight, discreet, and comfortable. If can be easily worn no with no discomfort, allowing patients to always receive the medication that they need. Every adhesive lined cartridge guarantees 24 hours of uninterrupted use.
During the 10 week smoking cessation program, Chrono Therapeutics offers a step down method. Most smokers begin with the highest strength of nicotine, 22 mg, and over the course of 10 weeks, step down to the lowest strength, 7mg, until they can fully go off nicotine. The delivery device uses a color coding technology that measures the level of nicotine, matching it to the progress charts that are synced with the behavioral support mobile application.
Bluetooth connection between the device and the smartphone allows the data to always be accessible, and provides timely, personalized reminders, helping the patient stay on track. Chrono also uses behavioral support, which is based on cutting-edge behavior change science and created alongside leading experts from the Mayo Clinic and Fred Hutchinson Cancer Research Center.
Chrono's integrated mobile coaching app is the key to successful long-term smoking cessation. Chrono’s wearable device has a “Crave” button. By simply pursuing it, the device discreetly records the craving and triggers immediate ‘just-in-time’ coaching. Delivered through the app, the feature is designed to help the smoker get through the craving without breaking their sobriety smoking.
